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doi: 10.1055/s-0030-1268417 21 FriedmanJ

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The industry's research findings do not meet FDA drug application data requirements

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At the molecular level, an increased protein level of claudin-2, a pore-forming claudin, was demonstrated in comparison to healthy controls, although these pores are of insufficient size to allow diffusion of bacterial products such as LPS in decompensated cirrhosis (4)