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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

New insights into molecular mechanisms of oxygen homeostasis

For example, severe neuroinflammation (brain fog) can dysregulate the autonomic nervous system, leading to worsened POTS symptoms (tachycardia), which in turn triggers mast cell degranulation (histamine release)

Pakharukova et al ., Reference Pakharukova, Ershov, Vorontsova, Katokhin, Merkulova and Mordvinov2012

In addition, astrocytes, which normally support neurons, become dysfunctional through a process called astrogliosis, which worsens glutamate imbalance and reduces neuronal support (Boille et al., 2006)

One last article was eliminated in final analysis because the laboratory methodology is now refuted by more recent scientific evidence