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It is required for a wide variety of reactions in amine and amino acid metabolism, and has been the subject of continuous mechanistic research since the 1930s

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e , In vivo tumor volume scatter plots on day 35 of sgControl and sgRASH3D19 PANC1 cells which were subcutaneously injected in nude mice (n=6 and 7 in the two groups) and treated daily with vehicle control or MRTX1133 at 3 mg/kg

Nature 588 , 479484 (2020)

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