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When activated, beta-3-AR triggers Gs protein coupling, adenylyl cyclase activation, cAMP production, protein kinase A phosphorylation, and hormone-sensitive lipase translocation to lipid droplets for triglyceride hydrolysis

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Parasutterella colonization has been shown to alter tryptophan, tyrosine, and xanthine metabolism in mouse cecal samples 61

Instead, it is focused more on fat-related pathways in the body

it is not FDA-approved and not for human consumption

This contradiction may be related to the individual differences of the subjects