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Because the production of anti-drug antibodies (ADAs) against biotherapeutics can have detrimental effects on drug safety, efficacy, and pharmacokinetics, immunogenicity an important factor in the toxicity profile of biotherapeutic proteins 16

If you're still unsure, the best way to decide which method is right for you is to talk to your doctor

Hunter, T

Author contributions Conceptualization: II, NA, and MM

Clinical Studies 14.1 Non-Squamous NSCLC Initial Treatment in Combination with Pembrolizumab and Platinum The efficacy of pemetrexed for injection in combination with pembrolizumab and platinum chemotherapy was investigated in Study KEYNOTE-189 (NCT02578680), a randomized, multicenter, double-blind, active-controlled trial conducted in patients with metastatic non-squamous NSCLC, regardless of PD-L1 tumor expression status, who had not previously received systemic therapy for metastatic disease and in whom there were no EGFR or ALK genomic tumor aberrations

It is the primary driver of autoimmune diseases like Hashimotos Thyroiditis