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Description

To investigate the role of GSS in male reproduction, we constructed Gss Flox/Flox mice by inserting two LoxP site to the left and right of exon 3 (Fig

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Kassar-Duchossoy L, et al

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However, as the development of multi-specific protein therapeutics becomes more widespread, the potential for immune complex formation and consequent immunogenicity must be considered, as the latter can lead to both loss of pharmacodynamic activity and safety concerns

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However, the precise mechanism by which NMT1 integrates into the dynamic environment of the translating ribosome, and how its co-translational activity is coordinated with that of both human MetAPs and other ribosome-associated enzymes remain unclear

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aureus is characterized by a lipid peroxidation mechanism where AA is oxidized into reactive electrophiles, which elicit toxicity by modifying the macromolecules of S

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Preclinical acute toxicity is low, with reported rodent LD50 values well above any human-equivalent research dose

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