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GI dysfunction, a common comorbidity in PD, further contributes to fluctuations in levodopa absorption and plasma concentrations, thereby triggering or exacerbating the on-off phenomenon [86, 87]

ChenSJiang PP YuDLiaoGCWuSLFangAPet al

These proteins contain an N-terminus bHLH domain that binds to DNA at specific sites (E-boxes) and a C-terminus Twist box domain that controls whether genes are turned on or off

Mitochondria-targeted catalase reverts the neurotoxicity of h SOD1G(9)(3) A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice

Food supplements should not be used as a substitute for a balanced diet and healthy lifestyle

Available diagnostic criteria Despite its high prevalence, there are still no universally accepted clinical criteria to characterise ME/CFS, making early and accurate diagnosis difficult (52)