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TPP has an enormous ionic radius owing to resonance-mediated diffusion of positive charge through three phenyl circles, which causes the unusual lipophilicity of TPP and transcendence from the membrane without a transporter 40

Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response, and worse survival in breast cancer

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Furthermore, arachidonic acid has been shown to inhibit oxidative stress by reducing mitochondrial membrane potential and blocking reverse electron transport (RET) through uncoupling, which in turn inhibits RET-dependent reactive oxygen species (ROS) generation (70)

10.1099/0022-1317-36-3-377 40 ZhaoM.VandersluisM.StoutJ.HauptsU.SandersM.JacquemartR

Chemical composition of Arbequina virgin olive oil in relation to extraction and storage conditions