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Univariate and multivariate analyses were performed using the KaplanMeier method or Cox proportional hazards regression

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This action, combined with the induction of GLT1 in astrocytes, may at least in part account for the beneficial effects of NAC in conditions associated with excessive release of glutamate and impairment of glutamate homeostasis, and characterized by maladaptive synaptic plasticity and excitotoxic neuronal death [113]

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