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By inhibiting IKK activity, it prevents IB degradation, NF-B nuclear translocation, and pro-inflammatory gene expression

High-fat-fed ApoE / mice exhibit larger atherosclerotic plaques, severe ferroptosis, increased NOX production, and reduced GSH and xCT expression in the thoracic aorta compared to wild-type mice ( / mice

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Iron, particularly organic iron, is a potent catalyst for lipid peroxidation and other free radical chain reactions

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