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Tzouvelekis A, Eickelberg O, Kaminski N, Bouros D, Aidinis V, editors

Thioredoxin inhibition The dysregulated TRX system often drives tumor progression and therapy resistance, making its targeted inhibition a potent ROS-mediated anticancer strategy

EGFR activation leads to an intracellular signaling cascade via Ras activation, which stimulates the extracellular signal pathway-regulated kinase/mitogen-activated protein kinase pathway