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A conjugate according to claim 1 or 2, wherein the ligand is a ligand that specifically binds to or is endocytosed or transcytosed into or through a BCEC or MDCK target cell at a rate that is at least 10% enhanced as compared control conditions selected from a) cells lacking expression of GSH transporters

[193] developed IFE-based fluorometric sensing and imaging of GSH using CDs directly as the IFE fluorophore and 5,5-dithiobis-(2-nitrobenzoic acid) (DTNB) as the recognition molecule for GSH

While effective, injections can be uncomfortable and create fluctuating, short-lived levels in the body

These findings indicate that IGF-1 therapy might be considered for amelioration of cell premature aging and liver fibrosis

If symptoms persist, discontinue use and consult a GP

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