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Research published in studies examining synaptic density following Dihexa administration found elevated synaptophysin and PSD-95 expressionmarkers of presynaptic and postsynaptic densitysustained for 714 days after a single administration cycle

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LBP was the only plasma marker consistently correlated with in vivo permeability measurement in both participants with healthy and higher body weight, showing a variation according to the group studied, from r = 0.423 in those with a healthy body weight up to r = 0.813 in the cohort with obesity [61]