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Inhibiting the system x C /glutathione axis selectively targets cancers with mutant-p53 accumulation

These factors substantially increase the risk of cardiovascular illnesses and lead to systemic metabolic disturbances [92]

& Skjonsberg, O

However, the manipulation of iron transporters through pro-inflammatory cytokines seems to impact only neurons and microglia, resulting in cellular iron overload in these specific cells [303,304,305]