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In contrast to what is normally expected, oxygen consumption by tumor mitochondria was low when pyruvate (Pyr) was oxidized because citrate produced by citrate synthase (CS) was mainly exported to the cytosol to support the active cholesterol biosynthesis, thus, decreasing citrate availability to oxidation through the conventional KC flux

NE-producing neurons in the LC widely project to many regions of the CNS to modulate functions such as attention, arousal, pain, mood, and stress responses (23, 24)

Astrocyte-like glioma cells exhibited profound alterations in mitochondrial metabolism, increased ROS production and high lipid peroxidation

Lehraiki A, Abbe P, Cerezo M, Rouaud F, Regazzetti C, Chignon-Sicard B, et al

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