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To identify glutathione-overproducing mutants, acrolein was used as a selective agent, given glutathiones key role in protecting cells from acrolein-induced toxicity (Mano et al., 2009

BDNF and GSK-3beta expression changes underlie the beneficial effects of crocin on behavioral alterations in a rat model of autism induced by prenatal valproic acid administration

However, due to the extensive cross-talk of KRAS-mediated signalling pathways, it is difficult to achieve effective inhibition of signalling pathways only by inhibiting a single key molecule, and joint inhibition of multiple key molecules is often required

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After that, plasma concentrations of NAC declined rapidly in both groups