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Three non-selective serotonin-receptor agonists were approved by FDA: fenfluramine (1973-1997), the combination phentermine-fenfluramine (1992-1997), and dexfenfluramine (1996-1997)

A.ShannonP.HaroutunianV.et al

TCIM, Traditional, Complementary, and Integrative Medicine

Pract Diab Int

Using SCLC NCI-H69 cells with and without HGF stimulation as the model, the screening arrays KPSS-1.3 and KPSS-2.0 together allowed detection of strong HGF-induction of specific phosphorylation sites in phosphoproteins downstream of c-MET itself, that are involved in diverse cellular regulation, including transcriptional control, cell cycle G 1 /S checkpoint, cell survival and apoptosis, cell proliferation and differentiation, stress and inflammatory response to cytokines and growth factors, as well as cytoskeletal functions

Additionally, vitamin B 12 deficiency can also occur as a result of other malabsorptive conditions (such as inflammatory bowel disease, or pancreatic insufficiency), after certain procedures (such as bariatric surgery, or ileal resection), restricted diets (such as veganism), or the use of certain medications (such as metformin or proton-pump inhibitors)