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Epigenetic factors in late-onset alzheimers disease: MTHFR and CTH gene polymorphisms, metabolic transsulfuration and methylation pathways, and b vitamins

The extracellular signalingregulated kinase (ERK) pathway is the most prominent and clinically utilized target, while the Jun N-terminal kinase (JNK) pathway and p38 pathway play critical modulatory roles in cancer cells

*Correspondence: Lingchen Tan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This observation was also seen in cells labeled with [U- 13 C]-glucose