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Icaritin was also reported to decrease intratumoral and splenic MDSCs, which are immunosuppressive cells dampening T cell cytotoxicity

Despite these advances, CAR-M research in AIDs remains largely preclinical, underscoring the need for clinical safety validation, and systemic CAR-M distribution, notably hepatic accumulation, poses risks of off-target toxicity and reduced efficacy (108)

Figures In Figs 2, 3, and 4, a trial named Onofrj, 1995 should not be included

Tryptophan and aryl hydrocarbon receptors as the target triad in Parkinsons disease-A narrative review