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Angiogenesis activation occurs via ROS mediated by hypoxia dependent and independent pathways

Optic nerve head blood flow, as measured by laser speckle flowgraphy, is significantly reduced in preperimetric glaucoma optic nerve head blood flow, as measured by laser speckle flowgraphy

These BDNF effects have since been replicated and extended in multiple subsequent studies

Statins are inhibitors of the MVA pathway, inhibit cholesterol synthesis [52], and are the most common lipid-lowering drugs used in clinical practice [53]

Previous research focused on elucidating the glucose-lowering mechanisms of metformin in the adipose tissue, muscle and liver of diabetic models 8,9

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