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Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia

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It was discovered in 1905 in Liebigs meat extracts, a popular dietary supplement at that time, by Gulewitsch and Krimberg [1] who named the substance from the Latin word for flesh (carnus)

This protective role is particularly important for cardiac cells

Loss of PRDX6 reduces GPX4 protein levels and sensitizes cells to ferroptosis