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retatrutide carries GLP-1 class risks including nausea, gallbladder disease, pancreatitis, and delayed gastric emptying affecting oral medicine absorption

[124] (Table S2 from Su et al., sheet S2.2 Metabolomics, age-, sex- and BMI-adjusted z-score-transformed plasma metabolite concentrations) and re-analysed the plasma metabolomics data for acetylcarnitine to investigate differences in acetylcarnitine levels between healthy controls and patients with PASC ( 1 PASC symptom according to the clinical information available from Table S1, sheet S1.3 PASC data of Su et al.)

These effects arise because it does not act solely on the skins MC1R receptor, but also stimulates other melanocortin receptor subtypes located in central regions of the brain

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