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Therefore, as expected we found increased mRNA expression of Gsr and other NRF2-regulated genes ( Gclm , Nqo1 , Srxn1 and Hmox1 ) (Fig 2A), as well as NRF2 and GSR protein abundance (Fig 2B) in LPS-stimulated RAW264.7 Ms with accumulated oxLDL

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Activation of adenosine A2A receptor up-regulates BDNF expression in rat primary cortical neurons

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The peptide Herdegradin, which downregulates EGFR, stimulates mitophagy through the mTORC2/Akt pathway, effectively inhibiting the growth of EGFR-positive cancers, such as PCa, ultimately inducing the death of PCa cells (Katreddy et al., 2018)

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