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The study reported no beneficial effect of Cerefolin NAC on glutathione levels, inflammatory cytokines or A42/A40 ratio compared to a placebo ( However, Cerefolin was observed to delay the progression of hippocampal and cortical atrophy in AD and related disorders patients as well as forebrain parenchymal atrophy in cerebrovascular disease patients with HHcy [107]

Without any memory loss and learning deficits, microglial TBK1 deficiency leads to social recognition impairments in mice at 4 months of age, resembling FTD symptoms