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JC70, Santa Cruz Biotechnology, United States) diluted in PBS containing 5% normal goat serum (NGS) and 0.02% Triton X-100

In those examples embodiments of antibody constructs of the invention are tested with respect to different stress conditions in different pharmaceutical formulations and the results compared with other half-life extending (HLE) formats of bispecific T cell engaging antibody construct known from the art

Morat, X

Using a synthetic mononucleosome substrate, the ability of RSC to promote nucleosome sliding can be monitored 29

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This process constructs a malignant positive feedback loop: released NETs act as thrombotic scaffolds to further capture circulating platelets and induce their activation, promoting further P-Exos release, and ultimately leading to widespread occlusion of pulmonary microvessels