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Several A-binding anticalins with high affinities and specificities for the monomeric A peptide target have recently been described 23 , and their mode of tight complex formation with the central A epitope (Lys P16 to Lys P28 )which is common to both A 40 and A 42 peptide specieswas elucidated by X-ray crystallography 24

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The Mayo Clinic indicates high doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling sensation in hands and feet Healthline says: In very rare cases, some people can experience side effects caused by allergic reactions or sensitivity In addition to helping athletes build muscle, vitamin B12 plays a role in maintaining nervous system function and brain health

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