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SKU: 46444799516
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Rating: 4.1053 (20 reviews)

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10.1021/cr200085w 21 DesaiP

Likewise, polyphenols or omega-3 fatty acid combinations with chemotherapy are studied for pharmacodynamic synergy by means of endpoints such as tumour volume reduction, progression-free survival and amelioration of chemotherapy-induced toxicity along with quality-of-life enhancement, keeping a close watch for antagonistic interactions or organ-specific adverse effects (234)

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In the context of type II diabetes, metformin-induced activation of AMPK leads to increased trafficking of GLUT transporters to increase glucose uptake and glycolysis, thereby, lowering blood glucose (Pernicova and Korbonits, 2014)