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This suggests that the application of any topical treatment may induce a localized inflammatory reaction in the initial phase

In cancer treatment, some widely used chemotherapeutic drugs (such as cisplatin, doxorubicin, arsenic trioxide (As 2 O 3 ), paclitaxel) enhance the apoptosis of cancer cells by inducing the production of intracellular ROS, prompting tumor cells to lose their ability to survive in an oxidative stress environment [466, 467]

Many therapeutic peptides require injection, so an orally active candidate is of particular research interest

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Additional protein factors aid in the initiation, elongation and termination of protein synthesis

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