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A negative vote typically results in the FDA issuing a final determination against listing, leaving the gray market as the only practical source though rejected substances can be re-nominated in future cycles or challenged in federal court

Significant group differences in the GPx activity were assessed using the chi-square test and the independent-samples median test, whereas for GSH and the GSH:GSSG ratio, the t-test for independent samples and analysis of variance (ANOVA) were used