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This surge in neurotransmitter production enhances synaptic transmission, improves neuronal communication, and helps lift the dense, disorienting brain fog that so many patients experience

the definition of this profile showed a good level of homogeneity (mean inter-item Spearman 0.25) [41] and has been extensively described previously as belonging to the immuno-metabolic depression (IMD) domain, based on previous findings on individual symptoms with immuno-metabolic dysregulation [2]

Improved insulin signaling helps the body process glucose more efficiently, reducing the tendency to store excess energy as fat

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doi: 10.1016/j.clnesp.2020.03.008