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Psoriasis and Vitamin D: A Systematic Review and Meta-Analysis

The former mainly exacerbate the inflammatory response by releasing the inflammatory factor IL-17, whereas Treg cells inhibit the activity of other immune cells by secreting anti-inflammatory cytokines, such as IL-1, IL-2, and transforming growth factor (TGF)-, which suppresses the activity of the antigen-presenting cells and T-cell function, reducing the production of inflammatory cytokines and antibodies (Li Z

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Th1 and Th2 are phenotypes of host-specific immune responses mediated by CD4 + T-lymphocytes in the pathogenesis of inflammatory diseases, and Th1/Th2 balance controls immune and inflammatory responses (Matia-Garcia et al., 2021)