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Coordinates and structural factors have been deposited in the Protein Data Bank (PDB ID: 7ZS3 (U19 APO ), 7ZVP (U19 GSH ), 7ZZN (U20 APO ), 8A08 (U20 GSH ), 8A0I (U20 GS-PAP ), 8A0Q (U20 BAI ), 8A0O (U20 GAL ), 8A0P (U20 MOR ), and 8A0R (U20 PIN ))

Functional group (FG) models To robustly assess the contribution of each FG, we computed consensus feature importances by averaging across the three tree-based MLs (Fig