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Kostoglou-Athanassiou I, Costa A, Navarra P, Nappi G, Forsling ML, Grossman AB

Orsborn, and J

This protective effect was mediated by the upregulation of Nrf2 mRNA expression, which alleviated oxidative stress (restoring GSH and GPX levels) and inflammatory responses (reflected in reduced TNF- and IL-6 levels) [99]

Additionally, statins are associated with an increased risk of type 2 diabetes mellitus (T2DM), although the mechanism underlying this side effect remains unclear

Current research is exploring the outcomes of paracetamol-related DILI cases and its relationship with liver transplantation as well as other treatment modalities