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Prognostic and predictive epigenetic biomarkers in oncology

Excessive lipid peroxidation contributes to plasma membrane damage and further triggering multiple cell death modalities

Heme is the prosthetic group for a number of proteins, including among others hemoglobin, myoglobin, mitochondrial cytochromes, microsomal cytochromes (including cytochrome P450), catalase, peroxidase, tryptophanpyrrolase, prostaglandin endoperoxide synthase, and the soluble form of guanylate cyclase

Similarly, no obvious poisoning symptoms were found, and no animals died within 14 days (Wu, 2009

Therefore, only MT-like cyclases are included in the following section, and the rest will be discussed in Section 3

Role of cyclooxygenase and protein kinase C