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Uncommon but notable adverse effects include: Hypokalaemia (low potassium) can occur during initial treatment of severe megaloblastic anaemia, as rapid cell production consumes potassium

This results in the cancer cells mistaking the antimetabolite medication for the ingredients they need

Specifically, we considered the usefulness of the estimated allowed amount, as defined at 180.20, in providing necessary context for the payer-specific negotiated charge and in facilitating comparisons across hospitals

However, until today no system could completely replace or outperform the activated sludge technology