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Fasting glucose is checked because GH can transiently affect insulin sensitivity, and a patient with prediabetes or undiagnosed metabolic syndrome requires a different clinical conversation

doi: 10.1016/j.bbalip.2013.10.008 6 AmbroggioE

In comparison, in an Ecuadorian kindred with GH receptor deficiency and very low levels of IGF-I, rates of cancer and diabetes were markedly reduced compared to unaffected people in the same communities (39)

Injections are more frequent because of improved absorption and bioavailability

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These are similar to those seen in younger adults with growth hormone deficiency