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It also has documented anti-inflammatory effects relevant to several types of hair loss, where chronic inflammation around follicles is a contributing factor

The degradation of branched-chain amino acids mainly occurs in the mitochondrial matrix, contributing to energy metabolism, mitochondrial biogenesis, as well as protein quality control in both mitochondria and cytosol

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AOD 9604 primarily affects pathways associated with lipid metabolism, including 3-adrenergic receptor signaling, cyclic AMPmediated cascades, and enzyme systems involved in lipolysis and lipogenesis

Cytokine release syndrome (CRS) was avoided by using an IgG4 isotype, which does not activate complement fixation (67)

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