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10.4111/kju.2012.53.3.200 Korean J

This effect has been validated in an in vivo study involving 14 cancer patients (10 with grade 2 CIPN and 4 with grade 3 CIPN) treated with docetaxel [149]

One of the most compelling pieces of evidence is the observed reduction in mitochondrial complex I activity in postmortem brains of PD patients, reinforcing mitochondrial involvement in PD pathology