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Othman BA, Ong JE, Dumitrescu AV (2022) Biallelic optic atrophy 1 (OPA1) related disorder-case report and literature review

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Effects of B12 Deficiency Vitamin B12 is a water-soluble micronutrient necessary for the formation of red blood cells and for the normal functioning of the central nervous system

The clinical consequence of elevated C4a includes post-exertional fatigue, migratory pain, and neurocognitive dysfunction, symptoms that often mirror mitochondrial dysfunction and autonomic dysregulation

Stimulated secretion of sIgA as a local defense mechanism can confirm this hypothesis, but more detailed studies about intestinal epithelial integrity and immunity are needed to extend knowledge regarding the complexity of microbiological, physiological and immunological processes in the gut