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Unlike the substrate-specific enzyme that hydrolyzes ThTP, synthesis of ThTP is currently known to be catalyzed only by the enzymes producing ATP through ADP phosphorylation

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For doses above 0.5mL, switch to 1mL or 3mL syringes larger syringes lose precision at small volumes but measure larger draws more reliably than overfilling a 0.5mL syringe

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While mild redness or bruising may occur around the treated areas, these effects and temporary and will fade with time