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In addition to oligonucleotide therapeutics, some small-molecule NNMT inhibitors have been reported recently [5659] and several have shown effectiveness in the prevention or treatment of obesity and T2D in vitro [60, 61] or in preclinical animal models [10, 58, 62], validating NNMT as a pharmacological drug target

Ailments like anemia and undergone gastrointestinal surgery patients also will not have absorption ability

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[4] [5] [6] [7] In general, patients with a documented sulfonamide allergy are considered to be predisposed for development of allergic drug reactions