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However, the mechanisms involved need to be further investigated in primary cell cultures

Real-world evidence featured prominently at EHA 2026, with new studies presented across multiple haematological conditions, including PNH, ITP, HLH, myelofibrosis, haemophilia, von Willebrand disease, and other rare disorders

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Furthermore, EVs were enriched for O -glycoproteins carrying the STn antigen compared with their parental cells, indicating selective packaging of STn-modified proteins into EVs and suggesting that STn might play a role in both EV release and cargo selection