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second, patients who were not eligible for LT

Allopurinol is generally well tolerated with rare but well described side effects that range from mild to potentially life threatening

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25 , 38 (1995) R.J

have shown that QP could promote IL-4 secretion by helper T cells, decrease IL-1 and TNF- expression, reduce production of reactive oxygen species by macrophages, and prevent caseous necrosis (Butov et al., 2016)

Strategies to boost the endogenous antioxidant defenses are highly desired