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2017;6:e356

The lyophilized peptide is reconstituted in a suitable solvent and injected into the system

This further exacerbates iron overload in lysosomes and promotes ferroptosis (An et al., Even so, multiple research suggests that by promoting the activity of the antioxidant gene superoxide dismutase 1 (SOD1), activating the nuclear transcription factor EB (TFEB) may prevent lysosome-based ferroptosis

(125) noted in their 2023 review that pCS and IS can upregulate nuclear factor-B (NF-B) activity, triggering pro-inflammatory processes and increasing reactive oxygen species (ROS) production, and may also play a role in colorectal cancer development and progression in CKD patients