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Also, p62 recruited to the damaged mitochondria ubiquitinates Mcl-1, leading to its degradation and activation of apoptosis [305]

It remains not clear why this surface residue Cys396, located far away from the monomer interaction could lead to monomerization

doi: 10.1016/j.redox.2022.102438 158 NitureSLinMQiQMooreJTLevineKEFernandoRAet al

Liquidliquid phase separation in atmospherically relevant particles consisting of organic species and inorganic salts

Common examples include: These are designed to mimic or enhance the bodys own signaling molecules while extending their activity through modifications like PEGylation , fatty acid chains , or amino acid substitutions

Apiradee U, Shina Q, Natdanai M, et al