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Description

Sandhoff disease (GM2 Gangliosidosis with stored GM2 Ganglioside) using targeted enzyme replacement therapy with beta-hexosaminidase A, or substrate inhibition of glucosylceramide synthase using imino sugars (e.g., miglustat (Zavesca marketed by Actelion) = N-butyl- deoxynojirimycin (NB-DNJ))

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6a), and the FBP-mediated conformational changes in RCC2 localized to a loop facing the presumed interface for Rac1 interaction (Fig

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PMID: 95 LanLWeiWZhengYNiuLChenXHuangDet al

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Prothrombotic factors do not increase the risk of recurrent ischemic events after cryptogenic stroke at young age: the FUTURE study

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This is due to several biological factors, including lower total body water, differences in alcohol dehydrogenase (ADH) activity, and hormonal influences 18

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