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10.3390/ijms26062479 71 HirayamaA.WakusawaK.FujiokaT.IwataK.UsuiN.KuritaD.et al (2020)

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The principal investigator, who serves as the lead researcher and main coordinator, along with the research physician, will be responsible for participant recruitment, treatment, and follow-up

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Recently, it has been demonstrated that inhibition of GDF15 counteracts cachexia by reducing activation of sympathetic nervous system on adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) in WAT, highlighting its major contribution in cachexia development besides appetite regulation (Suriben et al., 2020)