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These metabolic changes were supported by alterations in the gene expression of choline metabolism-related enzymes, such as choline dehydrogenase ( Chdh ), betaine-homocysteine methyltransferase ( Bhmt ), and DMG dehydrogenase ( Dmgdh ), and glycerophosphocholine phosphodiesterase 1 ( Gpcpd1 )

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Effect on ROS content in HaCaT cells Reactive oxygen species (ROS) radicals maintain a dynamic balance of continuous production and elimination in the human body and are essential for regulating normal physiological activities of the body 25

Nanotechnology not only improves aspirins delivery but also facilitates controlled and sustained drug release, which is crucial for maintaining therapeutic concentrations at the tumor site over extended periods

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DOI: 10.1016/j.jacc.2024.01.002 Long-Term Effects of LDL-C Lowering on Cardiovascular Risk This meta-analysis examines the long-term effects of LDL cholesterol reduction on cardiovascular risk, highlighting the stability of treatment effects over time