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Mutations in FUS, TDP-43, SOD1, and C9ORF72 increase DNA damage, alter mitochondria fusion and fission, alter calcium homeostasis, and reduce the activity of respiratory chain complexes II and IV (Kodavati et al., 2020

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Springer , Singapore Novaes RD, Mouro VG, Gonalves RV, Mendona AA, Santos EC, Fialho MC, Machado-Neves M (2018) Aluminum: A potentially toxic metal with dose-dependent effects on cardiac bioaccumulation, mineral distribution, DNA oxidation and microstructural remodeling