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doi: 10.3389/fphar.2024.1330797 Received 31 October 2023 Accepted 19 January 2024 Published 01 February 2024 Volume 15 - 2024 Edited by Sirajudheen Anwar, University of Hail, Saudi Arabia Reviewed by Talib Hussain, University of Hail, Saudi Arabia Rohit Kumar Tiwari, Sharda University, India Updates Copyright 2024 Buczyska, Sidorkiewicz, Krtowski and Adamska

The cells were then washed using MACS buffer (0.5% BSA + 2mM EDTA in PBS) followed by staining with different clones of anti-CD38: LS198-4-2 (Beckman Coulter), JK36 (Beckman Coulter) and HIT2 (BD Biosciences) for 10 mins in the dark at room temperature

RhIGF-1 resulted in significant, sustained increases in GFR (4281%) over a treatment period of 45 days

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